[Primary melanoma with multiple skin metastases].

accidental exposure. Kanerva et al9 described sensitization in 2 workers who suffered burns after exposure to MCI/ MI; within 24 hours these were complicated by allergic reactions. Patch testing was positive for MCI/MI. Other derivatives of isothiazolinone have also been shown to cause sensitization after accidental burns.13,14 Eczematous lesions appeared very rapidly (less than 120 hours) after the chemical burn. In this case, sensitization could have been caused at the time of the burn due to the quantity and purity of the chemical to which she was exposed, or because she had already become sensitized to the product by daily use (although the patient denied having previous skin lesions). Thus, it is impossible to establish when sensitization occurred as no patch tests were performed prior to the time of the burns.